Document Detail

Functional MRI-based therapeutic rTMS strategy for aphasic stroke patients: a case series pilot study.
MedLine Citation:
PMID:  20128673     Owner:  NLM     Status:  MEDLINE    
Four poststroke patients with motor-dominant aphasia received 10 treatment sessions of low-frequency repetitive transcranial magnetic stimulation (rTMS). Each treatment session consisted of 1,200 pulses of stimulation and the site of stimulation was an area homologous to the most activated site on functional MRI performed prior to rTMS. Consequently, rTMS was applied to the right frontal lobe in two patients and to the left frontal lobe in two patients. Treatment resulted in improvement of language function in all four patients. Our therapeutic rTMS strategy seems to be a clinically feasible neurorehabilitative approach for poststroke aphasic patients.
Wataru Kakuda; Masahiro Abo; Nobuyoshi Kaito; Motoi Watanabe; Atsushi Senoo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The International journal of neuroscience     Volume:  120     ISSN:  1563-5279     ISO Abbreviation:  Int. J. Neurosci.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-04     Completed Date:  2010-04-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  England    
Other Details:
Languages:  eng     Pagination:  60-6     Citation Subset:  IM    
Department of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, Japan.
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MeSH Terms
Aphasia / etiology,  pathology*,  therapy*
Brain / blood supply*,  physiopathology*
Brain Mapping*
Image Processing, Computer-Assisted / methods
Magnetic Resonance Imaging / methods
Middle Aged
Neuropsychological Tests
Oxygen / blood
Pilot Projects
Stroke / complications
Transcranial Magnetic Stimulation / methods*
Verbal Behavior / physiology
Reg. No./Substance:

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