| Functional MR angiography using phase contrast imaging technique at 3T MRI. | |
| | |
MedLine Citation:
|
PMID: 20083204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: Phase contrast magnetic resonance angiography (PC MRA) is an important, non-invasive method for obtaining quantitative information on blood flow. The purpose of the present study was to investigate the dynamic cerebral arterial response in humans to visual stimulation by quantitative velocity analysis using PC MRA. METHODS: Functional PC MRA (fPCA) images at 3 Tesla MRI were acquired with a total acquisition time of 10 m 18 s for 2 rest and 1 visual stimulation sessions using a flashing checker board. Twelve healthy subjects participated in this study. Circular regions of interest (ROIs) consisting of 21 pixels were analyzed to determine the velocity changes due to visual stimulation in selected vessel segments supplying the visual cortex. Time-of-flight (TOF) MRA and PC MRA reference volume images were then compared to measure the signal intensity and quantitative blood velocity changes in the cerebral vessels. RESULTS: The mean velocity changes measured by PC MRA between rest and stimulation were 0.64 and 0.42 cm/s within the peak ROI and distal ROIs of the selected blood vessels, which corresponds to a 42.9% and 30.1% increase, respectively. Both TOF MRA and PC MRA reference volume images also exhibited an increase in the signal intensity of the target vessels during stimulation. CONCLUSION: This study demonstrated that fPCA could play a role in the quantitative analysis of the functional cerebral vascular response by measuring dynamic vascular changes in intensity and velocity in small arteries. |
| | |
Authors:
|
Chang-Ki Kang; Sang-Hoon Kim; Hyon Lee; Chan-A Park; Young-Bo Kim; Zang-Hee Cho |
Related Documents
:
|
7909334 - The role of gallium scintigraphy, computerized tomogram scan, and magnetic resonance im... 17410714 - Evaluation of extracranial-intracranial bypass using quantitative magnetic resonance an... 21840264 - Diagnostic abilities of magnetic resonance imaging in traumatic injury to the posterior... 11274564 - Pulmonary arteriovenous malformations: three-dimensional gadolinium-enhanced mr angiogr... 21479894 - Imaging of mesothelioma. 10603614 - Multiple sclerosis: the disease and its manifestations. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-18 |
Journal Detail:
|
Title: NeuroImage Volume: 50 ISSN: 1095-9572 ISO Abbreviation: Neuroimage Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-03-01 Completed Date: 2010-06-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9215515 Medline TA: Neuroimage Country: United States |
Other Details:
|
Languages: eng Pagination: 1036-43 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, South Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Flow Velocity Cerebral Arteries / physiology* Cerebrovascular Circulation / physiology Feasibility Studies Female Humans Magnetic Resonance Angiography / instrumentation, methods* Magnetic Resonance Imaging / instrumentation, methods Male Photic Stimulation Rest Visual Cortex / blood supply, physiology* Visual Perception / physiology* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: COMT genotype affects prefrontal white matter pathways in children and adolescents.
Next Document: Impact of scatter correction on D(2) receptor occupancy measurements using (123)I-IBZM SPECT: Compar...