Document Detail

Function of the internal anal sphincter and rectal sensitivity in idiopathic constipation.
MedLine Citation:
PMID:  7128948     Owner:  NLM     Status:  MEDLINE    
Anal manometry was performed in 8 control individuals (group A) and in 13 patients with idiopathic constipation (group B), 6 of whom were grouped apart (group C) because of an elective delay of the intestinal transit in the rectum. The basal pressure of the internal anal sphincter, the rectal inflation volume necessary to elicit the rectoanal inhibitory reflex, and the duration of the reflex were not significantly different in the three groups, while the maximal amplitude of the reflex was significantly lower in group C at 10 and 100 cm3 of rectal distension. However, the amplitude of the sphincteric relaxation and the rectal inflation volumes were significantly correlated (p less than 0.001) in the three groups. The rectal sensitivity was lower in the patient groups and particularly in group C (p less than 0.05 vs. controls up to 50 cm3 of rectal distension). The results obtained do not support the 'outlet obstruction' hypothesis as a mechanism of idiopathic constipation and point out that rectal hyposensitivity seems to be the only abnormality in these patients, particularly in those with an elective delay of the transit in the rectum.
F Baldi; F Ferrarini; R Corinaldesi; R Balestra; M Cassan; G P Fenati; L Barbara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestion     Volume:  24     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  14-22     Citation Subset:  IM    
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MeSH Terms
Anal Canal / physiopathology*
Constipation / physiopathology*
Middle Aged
Rectum / physiopathology*
Reflex / physiology
Sensation / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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