Document Detail


Fulminant ulcerative colitis despite maximal immunosuppression following liver transplantation: a case report and literature review.
MedLine Citation:
PMID:  21939922     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inflammatory Bowel Disease (IBD) is thought to be the result of an overly aggressive immune response to ubiquitous antigens. Immuno -modulation and -suppression is therefore currently the treatment of choice. It was long anticipated that the course of pre-existing IBD should improve after orthotopic liver transplantation (OLT) due to increased immunosuppression. We report the case of a patient who developed acute fulminant colitis despite triple immunosuppression and mesalazine and review the relevant literature.
Authors:
Antony Pan; Martin Schlup; Ralf Lubcke; Michael Schultz
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2011-05-18
Journal Detail:
Title:  Journal of Crohn's & colitis     Volume:  5     ISSN:  1876-4479     ISO Abbreviation:  J Crohns Colitis     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-23     Completed Date:  2012-04-09     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101318676     Medline TA:  J Crohns Colitis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  465-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.
Affiliation:
Gastroenterology Unit, Southern District Health Board, Dunedin, New Zealand.
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MeSH Terms
Descriptor/Qualifier:
Cholangitis, Sclerosing / complications,  surgery*
Colectomy
Colitis, Ulcerative / etiology,  prevention & control*,  surgery
Drug Therapy, Combination
Female
Humans
Immunosuppressive Agents / therapeutic use*
Liver Transplantation*
Mesalamine / therapeutic use
Middle Aged
Mycophenolic Acid / analogs & derivatives,  therapeutic use
Prednisone / therapeutic use
Recurrence
Tacrolimus / therapeutic use
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents; 109581-93-3/Tacrolimus; 24280-93-1/Mycophenolic Acid; 53-03-2/Prednisone; 89-57-6/Mesalamine; 9242ECW6R0/mycophenolate mofetil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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