| Fulminant hepatic failure after repeated exposure to isoflurane. | |
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MedLine Citation:
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PMID: 21808406 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Inhalational agents are used routinely for maintenance of anaesthesia. Post anaesthesia hepatic failure has been documented following exposure to halothane. However, there are very few reports of such complications following isoflurane anaesthesia. A 6-year-old child developed fulminant hepatic failure 2 days following craniotomy under general anaesthesia. There was no evidence of viral, autoimmune, or metabolic causes of hepatitis. No other medications known to cause hepatitis, except low dose paracetamol, were administered. The clinical and histological picture of our case is similar to that of halothane hepatitis, which has a significant mortality rate. We report this as a possible fulminant hepatic failure resulting from exposure to isoflurane anaesthesia. |
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Authors:
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Halemani R Kusuma; Neelam K Venkataramana; Shailesh Av Rao; Arun L Naik; Ds Gangadhara; Keshavan H Venkatesh |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of anaesthesia Volume: 55 ISSN: 0976-2817 ISO Abbreviation: Indian J Anaesth Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-08-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0013243 Medline TA: Indian J Anaesth Country: India |
Other Details:
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Languages: eng Pagination: 290-2 Citation Subset: - |
Affiliation:
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Department of Anaesthesiology & Critical Care, BGS Global Hospitals, Bangalore, Karnataka, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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