Document Detail

Fulminant blastomycosis with blastomycotic infection of a cerebral glioma. Light microscopic and ultrastructural observations.
MedLine Citation:
PMID:  1767635     Owner:  NLM     Status:  MEDLINE    
Except for isolated case reports, blastomycosis has not been identified as a significant problem in immunosuppressed patients. We describe an unusual case with blastomycotic infection of a cerebral glioma in a 56-year-old man who underwent radiotherapy for his tumor and died of fulminant blastomycotic pneumonia. This is believed to be the first reported case of Blastomyces dermatitidis infection of a cerebral glioma. The light microscopic and ultrastructural features of B. dermatitidis, the giant forms of which were encountered in our patient, are described, and thr role of immunosuppression due to steroid therapy in the pathogenesis of this fulminant infection are reviewed.
V Jay; N Laperriere; R Perrin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neuropathologica     Volume:  82     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1991  
Date Detail:
Created Date:  1992-02-19     Completed Date:  1992-02-19     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  420-4     Citation Subset:  IM    
Department of Pathology, Ontario Cancer Institute/Hospital for Sick Children, University of Toronto, Canada.
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MeSH Terms
Blastomyces / isolation & purification
Blastomycosis / complications*
Brain Neoplasms / complications*,  microbiology,  pathology
Glioma / complications*,  microbiology,  pathology
Microscopy, Electron
Middle Aged
Tomography, X-Ray Computed

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