| Fulminant Wegener's granulomatosis presenting as epistaxis. | |
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MedLine Citation:
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PMID: 17351208 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case of a 63-year-old woman who presented to the emergency department with epistaxis and haemodynamic instability is reported. Subsequent investigation showed renal failure and multiple pulmonary nodules. A positive proteinase 3 antineutrophil cytoplasmic antibody test supported the diagnosis of fulminant Wegener's granulomatosis, requiring urgent dialysis, plasma exchange and immunosuppression. This is the first report in the emergency literature of Wegener's granulomatosis presenting as acute epistaxis. Emergency physicians should consider Wegener's granulomatosis in patients with atypical epistaxis. In patients presenting with clinically severe, active disease early proteinase 3 antineutrophil cytoplasmic antibody testing is recommended. |
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Authors:
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Ankur Thapar; Ajith George; Andrew Pfleiderer |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Emergency medicine journal : EMJ Volume: 24 ISSN: 1472-0213 ISO Abbreviation: Emerg Med J Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-03-12 Completed Date: 2007-06-05 Revised Date: 2010-09-15 |
Medline Journal Info:
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Nlm Unique ID: 100963089 Medline TA: Emerg Med J Country: England |
Other Details:
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Languages: eng Pagination: e14 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Peterborough & Stamford NHS Trust, Peterborough, UK. ankurthapar@doctors.org.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoantibodies
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analysis Biological Markers / analysis Epistaxis / etiology* Female Humans Kidney Failure, Chronic / etiology Lung Diseases / etiology, radiography Middle Aged Myeloblastin / immunology Tomography, X-Ray Computed Wegener Granulomatosis / complications*, diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Biological Markers; EC 3.4.21.76/Myeloblastin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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