Document Detail


Fulminant Wegener's granulomatosis presenting as epistaxis.
MedLine Citation:
PMID:  17351208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case of a 63-year-old woman who presented to the emergency department with epistaxis and haemodynamic instability is reported. Subsequent investigation showed renal failure and multiple pulmonary nodules. A positive proteinase 3 antineutrophil cytoplasmic antibody test supported the diagnosis of fulminant Wegener's granulomatosis, requiring urgent dialysis, plasma exchange and immunosuppression. This is the first report in the emergency literature of Wegener's granulomatosis presenting as acute epistaxis. Emergency physicians should consider Wegener's granulomatosis in patients with atypical epistaxis. In patients presenting with clinically severe, active disease early proteinase 3 antineutrophil cytoplasmic antibody testing is recommended.
Authors:
Ankur Thapar; Ajith George; Andrew Pfleiderer
Related Documents :
3935678 - Placental grade and pulmonary maturity in premature fetuses.
3064958 - Review of pulmonary brucellosis: a case report on brucellar pulmonary empyema.
9853728 - Pulmonary embolism and malpractice claims.
18813128 - Frequent expression of glypican-3 in merkel cell carcinoma: an immunohistochemical stud...
3935678 - Placental grade and pulmonary maturity in premature fetuses.
22106728 - Cutaneous mercury granuloma: a case report.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Emergency medicine journal : EMJ     Volume:  24     ISSN:  1472-0213     ISO Abbreviation:  Emerg Med J     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-03-12     Completed Date:  2007-06-05     Revised Date:  2010-09-15    
Medline Journal Info:
Nlm Unique ID:  100963089     Medline TA:  Emerg Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  e14     Citation Subset:  IM    
Affiliation:
Department of Otorhinolaryngology, Peterborough & Stamford NHS Trust, Peterborough, UK. ankurthapar@doctors.org.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Autoantibodies / analysis
Biological Markers / analysis
Epistaxis / etiology*
Female
Humans
Kidney Failure, Chronic / etiology
Lung Diseases / etiology,  radiography
Middle Aged
Myeloblastin / immunology
Tomography, X-Ray Computed
Wegener Granulomatosis / complications*,  diagnosis
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Biological Markers; EC 3.4.21.76/Myeloblastin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bradycardia in minor trauma: don't be slow on the uptake!
Next Document:  Lodged oesophageal button battery masquerading as a coin: an unusual cause of bilateral vocal cord p...