Document Detail

Fulminant, non-antibiotic associated Clostridium difficile colitis following Salmonella gastroenteritis.
MedLine Citation:
PMID:  20697966     Owner:  NLM     Status:  MEDLINE    
In the last decade there has been increasing awareness of the virulence and changing epidemiology of Clostridium difficile (C. difficile). While the vast majority of clinical cases of C. difficile are associated with antimicrobial or nosocomial exposure, this syndrome has been well described in the absence of antibiotic use. We present an unusual case of fatal, non-antibiotic associated C. difficile colitis following Salmonella serotype Saintpaul gastroenteritis in a previously healthy young person. We review the typical risk factors for C. difficile colitis and fulminant disease. We also review the epidemiology of community-acquired C. difficile-associated disease (CA-CDAD) and highlight Salmonella infection as a potential risk factor for development of CA-CDAD.
Stephanie A C Halvorson; Andrea S Cedfeldt; Alan J Hunter
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-08-10
Journal Detail:
Title:  Journal of general internal medicine     Volume:  26     ISSN:  1525-1497     ISO Abbreviation:  J Gen Intern Med     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-24     Completed Date:  2011-10-24     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8605834     Medline TA:  J Gen Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-7     Citation Subset:  IM    
Division of Hospital Medicine, Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
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MeSH Terms
Clostridium difficile* / pathogenicity
Endotoxins / adverse effects*
Enterocolitis, Pseudomembranous / diagnosis*,  etiology*,  microbiology
Gastroenteritis / complications,  diagnosis
Salmonella Infections / complications*,  diagnosis*
Young Adult
Reg. No./Substance:
0/Endotoxins; 0/salmonella toxin

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