Document Detail

Full spectrum of psychiatric disorders related to foreign migration: a Danish population-based cohort study.
MedLine Citation:
PMID:  23446644     Owner:  NLM     Status:  MEDLINE    
IMPORTANCE: Although increased risk for schizophrenia among immigrants is well established, knowledge of the broader spectrum of psychiatric disorders associated with a foreign migration background is lacking.
OBJECTIVE: To examine the full range of psychiatric disorders associated with any type of foreign migration background among persons residing in Denmark, including foreign-born adoptees, first- and second-generation immigrants, native Danes with a history of foreign residence, and persons born abroad to Danish expatriates.
DESIGN AND SETTING: Danish population-based cohort study. Persons were followed up from their 10th birthday for the development of mental disorders based on outpatient and inpatient data.
PARTICIPANTS: All persons born between January 1, 1971, and December 31, 2000 (N = 1 859 419) residing in Denmark by their 10th birthday with follow-up data to December 31, 2010.
MAIN OUTCOME MEASURES: Incidence rate ratios (IRRs) and cumulative incidences for psychiatric outcomes.
RESULTS: All categories of foreign migration background, except persons born abroad to Danish expatriates, were associated with increased risk for at least 1 psychiatric disorder. Foreign-born adoptees had increased IRRs for all psychiatric disorders and had the highest IRRs for these disorders compared with other foreign migration categories. First- and second-generation immigrants having 2 foreign-born parents had significantly increased IRRs for schizophrenia and schizophrenia spectrum disorders and had similar risk magnitudes. Second-generation immigrants having 1 foreign-born parent had significantly increased IRRs for all psychiatric disorders. Native Danes with a history of foreign residence had increased IRRs for bipolar affective disorder, affective disorders, personality disorders, and schizophrenia spectrum disorders.
CONCLUSIONS AND RELEVANCE: The extent to which a background of foreign migration confers an increased risk for the broad spectrum of psychiatric disorders varies according to parental origin, with greatest risks for foreign-born adoptees. The spectrum of psychiatric disorders showed greater variation within the second-generation immigrant group than between first-generation vs second-generation immigrants, and the spectrum differed according to whether individuals had 1 or 2 foreign-born parents.
Elizabeth Cantor-Graae; Carsten B Pedersen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JAMA psychiatry     Volume:  70     ISSN:  2168-6238     ISO Abbreviation:  JAMA Psychiatry     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-04     Completed Date:  2013-05-31     Revised Date:  2014-01-24    
Medline Journal Info:
Nlm Unique ID:  101589550     Medline TA:  JAMA Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  427-35     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Bipolar Disorder / epidemiology,  ethnology,  etiology
Cohort Studies
Denmark / epidemiology
Emigrants and Immigrants / psychology*
Mental Disorders / epidemiology,  ethnology,  etiology*
Mood Disorders / epidemiology,  ethnology,  etiology
Personality Disorders / epidemiology,  ethnology,  etiology
Risk Factors
Schizophrenia / epidemiology,  ethnology,  etiology
Sex Factors
Young Adult
Comment In:
JAMA Psychiatry. 2013 Dec;70(12):1374-5   [PMID:  24306814 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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