Document Detail


Fucose incorporation into rat hippocampus structures after acquisition of a brightness discrimination. A histoautoradiographic analysis.
MedLine Citation:
PMID:  516997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using a brigthness discrimination model in rats, the labeling of discrete hippocampus formation structures was studied after intraventricular application of [3H]-fucose. This substance was injected 5 min before training as well as 5 min, 3, 7 and 23 h after training, the pulse period lasting 120 min in all cases. A significantly training-related enhanced labeling of CA1, CA3 and CA4 cell bodies and fibres revealed that a biphasic time course occurring when radioactive fucose was applied 5 min before training and 7 h after training, whereas the increased labeling of area dentata structures was evidenced only after application of radioactive fucose 5 min before and after training. In all structures under investigation the training-related increase in labeling was more pronounced in the fibre layers than in the pyramidal and granular cell bodies.
Authors:
W Pohle; H L Rüthrich; N Popov; H Matthies
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta biologica et medica Germanica     Volume:  38     ISSN:  0001-5318     ISO Abbreviation:  Acta Biol. Med. Ger.     Publication Date:  1979  
Date Detail:
Created Date:  1980-02-15     Completed Date:  1980-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370276     Medline TA:  Acta Biol Med Ger     Country:  GERMANY, EAST    
Other Details:
Languages:  eng     Pagination:  53-63     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Autoradiography
Avoidance Learning
Fucose / metabolism*
Hippocampus / metabolism*
Light
Male
Prejudice*
Rats
Tissue Distribution
Tritium
Visual Perception*
Chemical
Reg. No./Substance:
10028-17-8/Tritium; 3713-31-3/Fucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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