Document Detail


FtsA is localized to the septum in an FtsZ-dependent manner.
MedLine Citation:
PMID:  8955398     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The localization of the cell division protein FtsA in E. coli was examined. FtsA was found to localize to the septum in a ring pattern as previously shown for FtsZ. The localization of FtsA was completely dependent on the localization of FtsZ. Under a variety of conditions that prevented formation of the Z ring, FtsA was unable to localize. In mutants where FtsZ forms structures in addition to Z rings, the pattern of FtsA duplicated these structures. These results suggest that the Z ring recruits FtsA to the septum.
Authors:
S G Addinall; J Lutkenhaus
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of bacteriology     Volume:  178     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-01-22     Completed Date:  1997-01-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  7167-72     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City 66160, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacterial Proteins / metabolism*
Cell Division
Cytoskeletal Proteins*
Escherichia coli / metabolism*
Escherichia coli Proteins*
Mutation
Rabbits
Grant Support
ID/Acronym/Agency:
GM29764/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Bacterial Proteins; 0/Cytoskeletal Proteins; 0/Escherichia coli Proteins; 0/FtsA protein, Bacteria; 0/FtsA protein, E coli; 0/FtsZ protein, Bacteria
Comments/Corrections

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