| Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men. | |
| | |
MedLine Citation:
|
PMID: 17284753 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Nutrients with antioxidant properties or that influence cell growth and differentiation might reduce the risk of benign prostatic hyperplasia (BPH). OBJECTIVE: The objective was to evaluate the association of fruit, vegetable, and micronutrient intakes with BPH. DESIGN: The participants were members of the Health Professionals Follow-Up Study and were aged 46-81 y in 1992. In 1992 and biennially thereafter, the men reported having surgery for an enlarged prostate, and in 1992 and on 3 subsequent questionnaires they completed the American Urological Association symptom index (AUASI). BPH cases were men who reported having surgery or who had an AUASI score of 15-35 (n = 6092). Control subjects were men who had not had surgery and never had an AUASI score >7 (n = 18 373). Men with a score of 8-14 were excluded (n = 7800). Intakes of fruit, vegetables, and antioxidants were assessed with a food-frequency questionnaire in 1986. We calculated odds ratios (ORs) of BPH and 95% CIs using logistic regression. RESULTS: Vegetable consumption was inversely associated with BPH (fifth compared with first quintile-OR: 0.89; 95% CI: 0.80, 0.99; P for trend = 0.03), whereas fruit intake was not. Consumption of fruit and vegetables rich in beta-carotene (P for trend = 0.004), lutein (P for trend = 0.0004), or vitamin C (P for trend = 0.05) was inversely related to BPH. With increasing vitamin C intake from foods, men were less likely to have BPH (P for trend = 0.0009). Neither alpha- nor gamma-tocopherol intake from foods was associated with BPH (P for trend = 0.05 and 0.84, respectively). CONCLUSION: Our findings are consistent with the hypothesis that a diet rich in vegetables may reduce the occurrence of BPH. |
| | |
Authors:
|
Sabine Rohrmann; Edward Giovannucci; Walter C Willett; Elizabeth A Platz |
Related Documents
:
|
15027093 - Paleoenvironmental basis of cognitive evolution in great apes. 9753793 - Dietary intake of trace elements and polycyclic aromatic hydrocarbons via vegetables gr... 22114713 - Allergenic lipid transfer proteins from plant-derived foods do not immunologically and ... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: The American journal of clinical nutrition Volume: 85 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 2007 Feb |
Date Detail:
|
Created Date: 2007-02-07 Completed Date: 2007-03-13 Revised Date: 2007-12-03 |
Medline Journal Info:
|
Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: 523-9 Citation Subset: AIM; IM |
Affiliation:
|
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Fruit* Humans Male Micronutrients / administration & dosage*, pharmacology* Middle Aged Odds Ratio Prostatic Hyperplasia / epidemiology*, prevention & control* Risk Factors United States / epidemiology Vegetables* |
| Grant Support | |
ID/Acronym/Agency:
|
CA55075/CA/NCI NIH HHS; DK44779/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Micronutrients |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Heme and non-heme iron consumption and risk of gallstone disease in men.
Next Document: Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at ...