Document Detail


Fructosylvaline. A simple model of the N-terminal residue of human haemoglobin A1c.
MedLine Citation:
PMID:  3993309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The phenylhydrazone of N-[D-fructosyl-(1)]-L-valine (1-deoxy-L-valine-D-fructose) was synthesized. The hydrazone was shown to exist in open form in basic solution and in closed form in acidic solution. The findings have bearings upon the discussion of the reaction of human haemoglobin A1c with phenylhydrazine.
Authors:
P Keil; H B Mortensen; C Christophersen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry     Volume:  39     ISSN:  0302-4369     ISO Abbreviation:  Acta Chem. Scand., B, Org. Chem. Biochem.     Publication Date:  1985  
Date Detail:
Created Date:  1985-06-20     Completed Date:  1985-06-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421265     Medline TA:  Acta Chem Scand B     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  191-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Hemoglobin A, Glycosylated / analysis*
Humans
Phenylhydrazines
Valine / analogs & derivatives*,  analysis
Chemical
Reg. No./Substance:
0/Hemoglobin A, Glycosylated; 0/Phenylhydrazines; 10003-64-2/fructosylvaline; 7004-03-7/Valine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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