| Fructose-induced breath hydrogen in patients with fruit intolerance. | |
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MedLine Citation:
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PMID: 18209585 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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GOALS: To measure bloating score, flatus passage, and hydrogen production after oral fructose in patients with history of fruit intolerance and compare these parameters with those in normal controls. BACKGROUND: Some patients complain of abdominal distention and excessive flatus after ingesting certain fruits such as mango, persimmon, and grapes but not after eating apricots and melon. STUDY: We recorded breath hydrogen, flatus passage and bloating after 20 g fructose in 8 patients with history of fruit intolerance and 4 healthy controls. Breath hydrogen was measured every 15 minutes for 480 minutes using EC-60 gastrolyzer. Number of passage of flatus was recorded over 8 hours. Severity of abdominal distention on a scale of 1 to 10 was noted. RESULTS: The patients with fruit intolerance produced breath hydrogen 1745.2+/-7.8 parts per million, passed flatus 13.8+/-0.3 times, and had bloating score of 5.7+/-0.1. The healthy controls produced breath hydrogen 712.5+/-5.8 parts per million in 8 hours, passed flatus 7.2+/-0.5 time, and had bloating score of 2.7+/-0.2. CONCLUSIONS: After 20 g fructose, patients with history of fruit intolerance produce more breath hydrogen, pass flatus more frequently, and have a higher bloating score compared with healthy controls. |
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Authors:
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Nirmal S Mann; Eddie C Cheung |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical gastroenterology Volume: 42 ISSN: 0192-0790 ISO Abbreviation: J. Clin. Gastroenterol. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-22 Completed Date: 2008-04-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7910017 Medline TA: J Clin Gastroenterol Country: United States |
Other Details:
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Languages: eng Pagination: 157-9 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, Davis School of Medicine, University of California, USA. nirmal.mann@ucdmc.ucdavis.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Breath Tests / methods* Dyspepsia / etiology*, physiopathology* Female Flatulence / etiology Fructose / metabolism* Fruit / adverse effects*, metabolism Humans Hydrogen / metabolism* Male Middle Aged Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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1333-74-0/Hydrogen; 30237-26-4/Fructose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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