Document Detail

Fructose increases the resistance of Rhodobacter capsulatus to the toxic oxyanion tellurite through repression of acetate permease (ActP).
MedLine Citation:
PMID:  21735076     Owner:  NLM     Status:  Publisher    
The highly toxic oxyanion tellurite (TeO(3) (2-)) enters the cells of the facultative photosynthetic bacterium Rhodobacter capsulatus through an acetate permease. Here we show that actP gene expression is down-regulated by fructose and this in turn determines a strong decrease of tellurite uptake and a parallel increase in the cells resistance to the toxic metalloid (from a minimal inhibitory concentration of 8 μM up to 400 μM tellurite under aerobic growth conditions). This demonstrates that there exists a direct connection between the level of tellurite uptake and the sensitivity of the cells to the oxyanion.
Roberto Borghese; Silvia Cicerano; Davide Zannoni
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-7
Journal Detail:
Title:  Antonie van Leeuwenhoek     Volume:  -     ISSN:  1572-9699     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372625     Medline TA:  Antonie Van Leeuwenhoek     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Biology, General Microbiology Unit, University of Bologna, via Irnerio 42, 40126, Bologna, Italy,
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