Document Detail

Frozen-thawed blastocyst transfer reduces ectopic pregnancy risk: an analysis of single embryo transfer cycles in Japan.
MedLine Citation:
PMID:  21377154     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate the effect of frozen-thawed blastocyst transfer on ectopic pregnancy (EP) rate. DESIGN: Retrospective analysis. SETTING: Japanese registry of assisted reproductive medicine. PATIENT(S): Women who were registered during 2008. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Rates of live birth, EP, and spontaneous abortion in single blastocyst and cleavage-stage ET cycles in both fresh and frozen-thawed were determined. RESULT(S): In the frozen-thawed single blastocyst transfer cycles, 84 EPs of 10,312 clinical pregnancies (0.81%) were reported. There were 25 EPs of 1,361 clinical pregnancies (1.8%) in fresh IVF single blastocyst transfer cycles and 19 of 1,352 (1.4%) in fresh intracytoplasmic sperm injection single blastocyst transfer cycles. The rate of EPs after frozen-thawed single blastocyst transfers varied between 0.56% and 0.97% after stratification by age group. CONCLUSION(S): Frozen-thawed blastocyst transfers have reduced EP rates significantly compared with fresh blastocyst transfers.
Osamu Ishihara; Akira Kuwahara; Hidekazu Saitoh
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-4
Journal Detail:
Title:  Fertility and sterility     Volume:  -     ISSN:  1556-5653     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology, Faculty of Medicine, Saitama Medical University, Saitama, Japan.
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