| Frontotemporal lobar degeneration: new understanding brings new approaches. | |
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MedLine Citation:
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PMID: 22284735 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Frontotemporal dementia (FTD) describes a group of clinical syndromes united by underlying frontotemporal lobar degeneration (FTLD) pathology. The clinical syndromes associated with FTLD are heterogeneous and are based on whether the patients present with behavioral, language, or motor impairments. FTLD is at the center of a paradigm shift in neurodegenerative diseases, with thought being given at diagnosis of underlying disease. There is pathologic heterogeneity of certain clinical syndromes such as behavioral variant FTD. Differentiation between the proteinopathies will become imperative as protein-specific treatments become available. This review provides an overview of FTLD, with an update of recent discoveries. |
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Authors:
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Maria Carmela Tartaglia |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neuroimaging clinics of North America Volume: 22 ISSN: 1557-9867 ISO Abbreviation: Neuroimaging Clin. N. Am. Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9211377 Medline TA: Neuroimaging Clin N Am Country: United States |
Other Details:
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Languages: eng Pagination: 83-97 Citation Subset: IM |
Copyright Information:
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Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Tanz Building, 6 Queen's Park Cres West, Room 231, Toronto, ON, Canada M5S 3H2. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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