Document Detail


Frontomaxillary facial angle at 11?+?0 to 13?+?6 weeks in Chinese population.
MedLine Citation:
PMID:  20593975     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objectives.?To establish the normal range of frontomaxillary facial (FMF) angle in the first trimester in a Chinese population. Methods.?In a prospective study from March 2007 to June 2007, three-dimensional (3D) volumes of the fetal profile in the mid-sagittal plane were recorded from 129 Chinese pregnant women who were screened for trisomy 21 by the combination of fetal nuchal translucency (NT) thickness, maternal serum free ?-human chorionic gonadotropin (?-hCG) and pregnancy-associated plasma protein-A (PAPP-A) at 11 to 13?+?6 weeks. 3D volumes were examined using multiplanar techniques. The FMF angle of each case was measured. The relationship between the measured FMF angle with the other parameter was also examined. Results.?The mean FMF angle decreased from 86.8? for a crown-rump length (CRL) of 45?mm to 76.0? for a CRL of 84?mm (FMF angle?=?99.49 ? 0.28?CRL, r?=(?)0.377, p?<?0.0001). There was no significant association between the FMF angle with serum PAPP-A or ?-hCG. The mean (SD) difference between FMF angle derived from Chinese formula and that from the published Caucasian equation was 1.47 (0.61) (95% CI 1.37?1.58) (p?<?0.0001). Conclusions.?In the first trimester, the FMF angle decreases with fetal CRL. There was similarity in the normal value of FMF angle between the Chinese and Caucasian populations.
Authors:
Min Chen; Hui Fang Wang; Tak Yeung Leung; Daljit Singh Sahota; Marisa Borenstein; Kypros Nicolaides; Terence Tzu-Hsi Lao; Tze Kin Lau
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Publication Detail:
Type:  Journal Article     Date:  2010-07-01
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  24     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  498-501     Citation Subset:  IM    
Affiliation:
Fetal Medicine Unit, Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
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