| Fronto-limbic dysfunction in borderline personality disorder: A 18F-FDG positron emission tomography study. | |
| | |
MedLine Citation:
|
PMID: 21272937 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
INTRODUCTION: Several functional neuroimaging studies have demonstrated abnormalities in fronto-limbic pathways when comparing borderline personality disorder (BPD) patients with controls. The present study aimed to evaluate regional cerebral metabolism in euthymic BPD patients with similar measured impulsivity levels by means of 18F-FDG PET during resting state and to compare them against a control group. METHODS: The present study evaluates regional cerebral metabolism in 8 euthymic BPD patients with 18F-FDG PET during resting state as compared to 8 controls with similar socio-geographic characteristics. RESULTS: BPD patients presented a marked hypo-metabolism in frontal lobe and showed hyper-metabolism in motor cortex (paracentral lobules and post-central cortex), medial and anterior cingulus, occipital lobe, temporal pole, left superior parietal gyrus and right superior frontal gyrus. No significant differences appeared in basal ganglia or thalamus. CONCLUSIONS: Results reveal a dysfunction in patients' frontolimbic network during rest and provide further evidence for the importance of these regions in relation to BPD symptomatology. |
| | |
Authors:
|
José Salavert; Miquel Gasol; Eduard Vieta; Ana Cervantes; Carlos Trampal; Juan Domingo Gispert |
Related Documents
:
|
402187 - Effect of thymosin in vitro on t cell levels during radiation therapy: correlations wit... 838757 - Lymphocyte transformation in lung cancer patients. 21222127 - Clinically overt and silent cerebral embolism in the course of infective endocarditis. 6979447 - Peripheral blood t lymphocytes in patients with duodenal ulcers treated with cimetidine. 17186287 - Pituitary-adrenal responses to human corticotropin-releasing hormone in critically ill ... 9381547 - Clinical significance of renal allograft biopsies with "borderline changes," as defined... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-1-25 |
Journal Detail:
|
Title: Journal of affective disorders Volume: - ISSN: 1573-2517 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2011-1-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7906073 Medline TA: J Affect Disord Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier B.V. All rights reserved. |
Affiliation:
|
Borderline Personality Disorder Institute, Psychiatry Department, Capio Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, Spain; Psychiatry Department, Hospital San Rafael, H Univ Vall d'Hebron, Barcelona, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Histopathological effects and EROD induction in common carp exposed to dietary heavy oil.
Next Document: Full and partial PTSD among young adult survivors 10months after the L'Aquila 2009 earthquake: Gende...