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Frontline antibiotic therapy.
MedLine Citation:
PMID:  23760700     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The need to use front-line antibiotics wisely has never been greater. Antibiotic resistance and multi-drug resistant infection, driven by antibiotic use, remain major public health and professional concerns. To overcome these infection problems, use of older antibiotics active against multi drug-resistant pathogens is increasing - for example, colistin, fosfomycin, pivmecillinam, pristinamycin, temocillin and oral tetracyclines. The number of new antibacterials reaching clinical practice has reduced significantly in the last 20 years, most being focused on therapy of Gram-positive infection - eg linezolid, daptomycin, telavancin and ceftaroline. Recent guidance on antibiotic stewardship in NHS trusts in England is likely to provide a backdrop to antibiotic use in hospitals in the next 5 years.
Authors:
Alasdair Macgowan; Maha Albur
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical medicine (London, England)     Volume:  13     ISSN:  1470-2118     ISO Abbreviation:  Clin Med     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-06-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092853     Medline TA:  Clin Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  263-8     Citation Subset:  IM    
Affiliation:
Bristol Centre for Antimicrobial Research & Evaluation, University of Bristol, UK.
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