| Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei. | |
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MedLine Citation:
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PMID: 17512950 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient developed frontal-lobe syndrome and psychotic symptoms after infarction in the pontomesencephalic junction. Stereotaxic lesion localization on magnetic resonance imaging and statistical analyses of regional cerebral blood flow (rCBF) disclosed an involvement of the rostral brainstem dopaminergic nuclei and hypoperfusion in the frontal-subcortical circuit components. We suggest that the patient's cognitive and behavioral disturbances were associated with disruption of ascending dopaminergic projections to the frontal-subcortical circuits. |
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Authors:
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Yoshiyuki Nishio; Kazunari Ishii; Hiroaki Kazui; Yoshiyuki Hosokai; Etsuro Mori |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2007-05-21 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 260 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-08-13 Completed Date: 2007-12-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 271-4 Citation Subset: IM |
Affiliation:
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Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan. nishiou@mail.tains.tohoku.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Brain Mapping Brain Stem / metabolism, physiopathology*, radionuclide imaging Brain Stem Infarctions / complications, physiopathology Cerebrovascular Circulation / physiology Dementia / etiology, physiopathology*, radionuclide imaging Dopamine / metabolism* Female Frontal Lobe / metabolism, physiopathology*, radionuclide imaging Humans Magnetic Resonance Imaging Neural Pathways / metabolism, physiopathology*, radionuclide imaging Pons / metabolism, physiopathology, radionuclide imaging Psychotic Disorders / etiology, physiopathology*, radionuclide imaging Tegmentum Mesencephali / metabolism, physiopathology, radionuclide imaging Tomography, Emission-Computed, Single-Photon |
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