Document Detail

Frontal lobe lesions and cognitive function in craniopharyngioma survivors.
MedLine Citation:
PMID:  3717109     Owner:  NLM     Status:  MEDLINE    
We performed neuropsychological testing using the Luria-Nebraska Neuropsychological Battery, computed tomography, and magnetic resonance imaging (MRI) in four patients one to 15 years after surgery and radiation therapy for childhood craniopharyngioma. Of three patients with impairment of frontal lobe-mediated cognitive function, two had extensive areas of prolonged spin-lattice and spin-spin relaxation times in the frontal lobes demonstrated by MRI, and one had a lipid accumulation in the anterior horn of the right lateral ventricle and beneath a burrhole defect in the skull. One patient with minimal cognitive dysfunction had no abnormality in imaging studies. We believe assessment of neuropsychological status is an important aspect of the evaluation of children with craniopharyngioma. We have found the Luria-Nebraska Neuropsychological Battery and MRI to be particularly useful in this evaluation.
M W Stelling; S E McKay; W A Carr; J W Walsh; R J Baumann
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  140     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-07-21     Completed Date:  1986-07-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  710-4     Citation Subset:  AIM; IM    
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MeSH Terms
Cognition Disorders / diagnosis*,  pathology
Craniopharyngioma / pathology*
Follow-Up Studies
Frontal Lobe / pathology*
Magnetic Resonance Spectroscopy / diagnostic use
Neoplasm Invasiveness
Pituitary Neoplasms / pathology*
Psychological Tests
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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