| Frontal lobe degeneration and Alzheimer's disease: a controlled study on clinical findings, volumetric brain changes and quantitative electroencephalography data. | |
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MedLine Citation:
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PMID: 8788079 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ten patients with a clinical diagnosis of frontal lobe degeneration (FLD) were compared with a group of patients with probable Alzheimer's disease (AD) and with nondemented controls matched for gender and age. In comparison with AD, the duration of illness was slightly shorter and cognitive performance was better in patients with FLD. The greatest enlargement of cerebrospinal fluid volumes was found in FLD and this effect was most pronounced in the anterior fissure and lateral ventricles. Estimates of EEG band-power and EEG coherence in FLD were not remarkably different from nondemented controls, whereas delta- and theta-power were significantly increased in AD. These observations may indicate different disease processes with a dissociation of volumetric computed tomography and quantitative EEG changes, which may be of differential diagnostic value. |
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Authors:
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H Förstl; C Besthorn; F Hentschel; C Geiger-Kabisch; H Sattel; U Schreiter-Gasser |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Dementia (Basel, Switzerland) Volume: 7 ISSN: 1013-7424 ISO Abbreviation: Dementia Publication Date: 1996 Jan-Feb |
Date Detail:
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Created Date: 1996-10-31 Completed Date: 1996-10-31 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9010348 Medline TA: Dementia Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 27-34 Citation Subset: IM |
Affiliation:
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Central Institute of Mental Health, Mannheim, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Alzheimer Disease / cerebrospinal fluid, pathology*, radiography Atrophy / pathology Behavior / physiology Case-Control Studies Cognition / physiology Electroencephalography* Female Frontal Lobe / pathology*, radiography Humans Male Middle Aged Prospective Studies Psychiatric Status Rating Scales Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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