| From the regulation of peptidoglycan synthesis to bacterial growth and morphology. | |
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MedLine Citation:
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PMID: 22203377 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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How bacteria grow and divide while retaining a defined shape is a fundamental question in microbiology, but technological advances are now driving a new understanding of how the shape-maintaining bacterial peptidoglycan sacculus grows. In this Review, we highlight the relationship between peptidoglycan synthesis complexes and cytoskeletal elements, as well as recent evidence that peptidoglycan growth is regulated from outside the sacculus in Gram-negative bacteria. We also discuss how growth of the sacculus is sensitive to mechanical force and nutritional status, and describe the roles of peptidoglycan hydrolases in generating cell shape and of D-amino acids in sacculus remodelling. |
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Authors:
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Athanasios Typas; Manuel Banzhaf; Carol A Gross; Waldemar Vollmer |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-28 |
Journal Detail:
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Title: Nature reviews. Microbiology Volume: - ISSN: 1740-1534 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101190261 Medline TA: Nat Rev Microbiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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1] Department of Microbiology & Immunology, University of California, San Francisco. [2] Genome Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg 69117, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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