Document Detail


From medical images to multiple-biomarker microarrays.
MedLine Citation:
PMID:  18196819     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A favorite cliché, often attributed to Yogi Berra, is "Prediction is difficult, especially about the future!" In this brief review, we shall recall some historical difficulties in predicting the future of diagnostic medical imaging--in particular, the modern technologies of CT and MRI--and examine the analogous situation in the emerging technology of diagnostic microarrays for the multiple-biomarker problem. All of these technologies began their lives as ill-conditioned problems, i.e., there was insufficient data to solve the central problem at hand.
Authors:
Robert F Wagner
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Medical physics     Volume:  34     ISSN:  0094-2405     ISO Abbreviation:  Med Phys     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-01-16     Completed Date:  2008-08-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425746     Medline TA:  Med Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4944-51     Citation Subset:  IM    
Affiliation:
Center for Devices and Radiological Health, FDA, 10903 New Hampshire Avenue, Building 62, Room 3126, Silver Spring, Maryland 20993-0002, USA.
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MeSH Terms
Descriptor/Qualifier:
Biological Markers*
Genomics / trends
Humans
Leukemia / genetics
Magnetic Resonance Imaging / trends*
Microarray Analysis / trends*
Tomography, X-Ray Computed / trends*
Chemical
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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