Document Detail

From exercise intolerance to functional improvement: the second wind phenomenon in the identification of McArdle disease.
MedLine Citation:
PMID:  25054987     Owner:  NLM     Status:  In-Data-Review    
McArdle disease is the most common of the glycogen storage diseases. Onset of symptoms is usually in childhood with muscle pain and restricted exercise capacity. Signs and symptoms are often ignored in children or put down to 'growing pains' and thus diagnosis is often delayed. Misdiagnosis is not uncommon because several other conditions such as muscular dystrophy and muscle channelopathies can manifest with similar symptoms. A simple exercise test performed in the clinic can however help to identify patients by revealing the second wind phenomenon which is pathognomonic of the condition. Here a patient is reported illustrating the value of using a simple 12 minute walk test.
Renata Siciliani Scalco; Sherryl Chatfield; Richard Godfrey; Jatin Pattni; Charlotte Ellerton; Andrea Beggs; Stefen Brady; Andrew Wakelin; Janice L Holton; Ros Quinlivan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  72     ISSN:  1678-4227     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  538-41     Citation Subset:  IM    
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