| From the decidual cell internet: trophoblast-recognizing T cells. | |
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MedLine Citation:
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PMID: 9915985 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The mammalian fetus has been perceived, paradoxically, as a successful allograft, a successful tumor, and a successful parasite. Success depends on fetal trophoblast cells, which form the interface with the mother. The maternal immune system is involved in the success of pregnancy and in its failure. The discovery that maternal gammadelta T cells may recognize and react to the fetal trophoblast and the definition of a vascular mechanism whereby their Th1 and Th2/3-type cytokines may abort embryos replaces confusion and debate with a new and simple clarity that enables further research. |
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Authors:
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P Arck; J Dietl; D Clark |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Biology of reproduction Volume: 60 ISSN: 0006-3363 ISO Abbreviation: Biol. Reprod. Publication Date: 1999 Feb |
Date Detail:
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Created Date: 1999-04-13 Completed Date: 1999-04-13 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0207224 Medline TA: Biol Reprod Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 227-33 Citation Subset: IM |
Affiliation:
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Charité, Campus Virchow Klinikum, Humbolt University, 13353 Berlin, Germany. petra.arck@charite.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antigens / immunology Decidua / immunology* Female Humans Killer Cells, Natural / immunology Pregnancy Receptors, Antigen, T-Cell, gamma-delta / analysis, immunology T-Lymphocytes / immunology* Trophoblasts / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Antigens; 0/Receptors, Antigen, T-Cell, gamma-delta |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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