Document Detail

From childhood to adult age: 18-year longitudinal results and prediction of the course of mental disorders in the community.
MedLine Citation:
PMID:  19212695     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This prospective longitudinal study of a representative community sample of children and adolescents (N = 269) examined the long-term course and predictive power of psychiatric symptoms in childhood/adolescence for diagnostic outcome (ICD-10) 18 years later at adult age. METHOD: At both cross-sectional assessments, baseline (1980-1984) and the 18-year follow-up (2001-2004), psychiatric symptoms were assessed using the 'Standardized Psychiatric Interview' (Goldberg et al. in Br J Prev Soc Med 24:18-23, 1970). At follow-up, study participants were reassessed with the standardized M-CIDI (Wittchen and Pfister in Manual und Durchführungsbeschreibung des DIA-X-M-CIDI, Swets and Zeitlinger, Frankfurt, 1997) interview. RESULTS: The participation rate at 18-year follow-up was 82% of those alive. The frequency of clinically relevant depressive symptoms and symptoms of anxiety or phobia was considerably higher when the participants were younger (baseline assessment at childhood, adolescent age) as compared to their scores in adult age. Increased levels of somatic symptoms, fatigue, irritability, sleep disturbances, depression, anxiety and worry as well as phobic symptoms in childhood/adolescence were related to a higher risk of suffering from a psychiatric disorder in adulthood. Depressive symptoms predicted both mood disorders and substance use disorders in adulthood. Phobias predicted later anxiety disorders. CONCLUSION: These data spanning almost two decades add significant information to the existing literature on the course of mental disorders in the community during the transition from adolescence to adulthood.
Manfred M Fichter; Gabriele Kohlboeck; Norbert Quadflieg; Anne Wyschkon; Günter Esser
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-02-11
Journal Detail:
Title:  Social psychiatry and psychiatric epidemiology     Volume:  44     ISSN:  1433-9285     ISO Abbreviation:  -     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-28     Completed Date:  2009-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804358     Medline TA:  Soc Psychiatry Psychiatr Epidemiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  792-803     Citation Subset:  IM    
Dept. of Psychiatry, University of Munich, Munich, Germany.
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MeSH Terms
Age Factors
Child, Preschool
Data Collection / statistics & numerical data
Depressive Disorder / diagnosis,  epidemiology
Follow-Up Studies
Germany / epidemiology
International Classification of Diseases
Longitudinal Studies
Mental Disorders / diagnosis*,  epidemiology
Outcome Assessment (Health Care)
Personality Inventory
Phobic Disorders / diagnosis,  epidemiology
Prospective Studies
Psychiatric Status Rating Scales
Sex Factors
Substance-Related Disorders / diagnosis,  epidemiology

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