| From beans to berries and beyond: teamwork between plant chemicals for protection of optimal human health. | |
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MedLine Citation:
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PMID: 17986598 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is now well known to consumers around the world that certain fruits and vegetables can help prevent or treat chronic human diseases. But, what many people don't fully appreciate is that it is not a single component in these plant-derived foods, but rather complex mixtures of interacting natural chemicals, that produce such powerful health-protective effects. These natural components accumulate simultaneously together in a plant, and provide a multifaceted defensive strategy for both the plant, and the human consumer. In order to investigate the strength of natural chemical cooperation in highly-pigmented, flavonoid-rich functional foods, our lab has relied on analysis of both whole fruits, and continuous, reliable plant cell culture production systems which accumulate anthocyanins and proanthocyanidins in high concentrations. Successive rounds of relatively gentle, rapid, and large-volume fractionations are linked to bioassay of complex to simple mixtures and semi-purified compounds. By means of this strategy, additive interactions or synergies between related compounds in health maintenance can be sorted out. Interestingly, phytochemical interactions between the same classes of compounds intensify the efficacy of flavonoid-rich fruits against multiple, not necessarily discrete, human disease conditions including CVD, cancer, metabolic syndrome, and others. |
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Authors:
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Mary Ann Lila |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annals of the New York Academy of Sciences Volume: 1114 ISSN: 0077-8923 ISO Abbreviation: Ann. N. Y. Acad. Sci. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-11-07 Completed Date: 2008-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7506858 Medline TA: Ann N Y Acad Sci Country: United States |
Other Details:
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Languages: eng Pagination: 372-80 Citation Subset: IM |
Affiliation:
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Division of Nutritional Sciences, University of Illinois, 211 Mumford Hall MC 710, 1301 W. Gregory Drive, Urbana, IL 61801, USA. imagemal@uiuc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Diet, Vegetarian* Fabaceae / chemistry*, physiology Fruit / chemistry*, physiology Humans Nutritive Value Phytotherapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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