| From analytic inversion to contemporary IMRT optimization: Radiation therapy planning revisited from a mathematical perspective. | |
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MedLine Citation:
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PMID: 21616694 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In this paper we look at the development of radiation therapy treatment planning from a mathematical point of view. Historically, planning for Intensity-Modulated Radiation Therapy (IMRT) has been considered as an inverse problem. We discuss first the two fundamental approaches that have been investigated to solve this inverse problem: Continuous analytic inversion techniques on one hand, and fully-discretized algebraic methods on the other hand. In the second part of the paper, we review another fundamental question which has been subject to debate from the beginning of IMRT until the present day: The rotation therapy approach versus fixed angle IMRT. This builds a bridge from historic work on IMRT planning to contemporary research in the context of Intensity-Modulated Arc Therapy (IMAT). |
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Authors:
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Yair Censor; Jan Unkelbach |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-24 |
Journal Detail:
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Title: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) Volume: - ISSN: 1724-191X ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9302888 Medline TA: Phys Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Mathematics, University of Haifa, Mt. Carmel, Haifa 31905, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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