Document Detail

From GH to Billy Ghrelin.
MedLine Citation:
PMID:  19656485     Owner:  NLM     Status:  MEDLINE    
The octanoylated peptide hormone ghrelin regulates episodic growth hormone release and energy balance. Work in genetically modified mice (Kirchner et al., 2009) now shows that in vivo activity of ghrelin O-acyltransferase (GOAT), responsible for ghrelin octanoylation, decreases during fasting but increases after ingesting medium-chain fatty acid triglycerides (MCT).
Roy G Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell metabolism     Volume:  10     ISSN:  1932-7420     ISO Abbreviation:  Cell Metab.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-06     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101233170     Medline TA:  Cell Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  82-3     Citation Subset:  IM    
Department of Metabolism and Aging, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
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MeSH Terms
Acyltransferases / deficiency,  genetics,  metabolism
Ghrelin / genetics,  metabolism*
Growth Hormone / metabolism*
Mice, Transgenic
Receptors, Ghrelin / metabolism
Reg. No./Substance:
0/Ghrelin; 0/Receptors, Ghrelin; 9002-72-6/Growth Hormone; EC 2.3.-/Acyltransferases; EC 2.3.-/ghrelin O-acyltransferase, mouse

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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