| Fresh Frozen Plasma for Progressive and Refractory Angiotensin-Converting Enzyme Inhibitor-induced Angioedema. | |
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MedLine Citation:
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PMID: 23114109 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Angioedema secondary to angiotensin-converting enzyme inhibitors (ACEI) is a commonly encountered problem in the Emergency Department (ED). The treatment of ACEI-induced edema with conventional methods such as epinephrine, steroids, and antihistamines is usually not effective. There is limited experience using bradykinin receptor blockers and fresh frozen plasma (FFP) as a treatment modality for ACEI-induced angioedema. OBJECTIVE: To emphasize alternative treatment option for ACEI-induced angioedema in the ED. CASE REPORTS: We report a case series of progressive and refractory presumed ACEI-induced angioedema that all improved in temporal association with administration of FFP, with a brief review of the literature. CONCLUSION: There was a temporal association between the administration of FFP and improvement in angioedema in seven cases of presumed ACEI-induced angioedema that were refractory to antihistamines, corticosteroids, and epinephrine. |
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Authors:
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Getaw Worku Hassen; Hossein Kalantari; Monica Parraga; Roger Chirurgi; Carlos Meletiche; Christopher Chan; Jacque Ciarlo; Farhad Gazi; Christopher Lobaito; Siamak Tadayon; Selamawit Yemane; Carolina Velez |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-28 |
Journal Detail:
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Title: The Journal of emergency medicine Volume: - ISSN: 0736-4679 ISO Abbreviation: J Emerg Med Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-11-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8412174 Medline TA: J Emerg Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Department of Emergency Medicine, New York Medical College, Metropolitan Hospital Center, New York, New York. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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