Document Detail


Frequent ventricular ectopic activity without underlying cardiac disease: analysis of 45 subjects.
MedLine Citation:
PMID:  6195910     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty-five subjects, aged 2 weeks to 62 years, who presented with frequent (greater than 100/day) ventricular ectopic beats (VEBs) and without evidence of underlying cardiac disease were studied. The spectrum of ventricular dysrhythmia was assessed by 24-hour ambulatory electrocardiography and exercise tolerance test. Sinus rhythm was the prevailing rhythm in all subjects. VEB frequency averaged 444 +/- 454 per hour (range 0 to 1,863) over the 24-hour monitoring period and was not significantly different during waking or sleeping periods. There was no simple correlation of VEB frequency with prevailing sinus rate (r = -0.0006; p = not significant [NS]). The prevalence of complex VEBs (multiform, R-on-T and repetitive) was relatively high (18 of 45 patients), and was equally distributed about the median VEB frequency of 314 VEBs/hour (7 of 18 versus 11 of 18; NS). Of the 43 subjects who had exercise tests, 37 had VEBs during the preexercise rest phase, compared with only 11 at peak exercise (p less than 0.0001). To assess the short-term natural history of the VEBs, 27 subjects had repeat clinical examinations and 24-hour electrocardiograms at a mean interval of 8 months. All remained well. Although there was considerable individual temporal variability of VEB frequency in this subgroup, there was no significant change in group mean values (415 +/- 409 VEBs/hour initially versus 401 +/- 383 VEBs/hour at follow-up study; NS). The relative temporal constancy of VEB frequency in the group as a whole was also reflected in a high linear correlation of VEB frequency at initial and follow-up studies (r = 0.816; p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
T J Montague; D D McPherson; B R MacKenzie; C A Spencer; M A Nanton; B M Horacek
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  52     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  980-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cardiac Complexes, Premature / diagnosis*
Child
Child, Preschool
Electrocardiography
Female
Heart Diseases / diagnosis*
Heart Rate
Humans
Infant
Infant, Newborn
Male
Middle Aged
Monitoring, Physiologic
Physical Exertion
Risk

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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