| Frequent administration of uric acid extends survival of fasting analbuminemic rats under cold environment. | |
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MedLine Citation:
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PMID: 3735794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Analbuminemic rats died within 18 h after a rapid decrease of body temperature whereas control Charles River, Wistar, and Sprague Dawley rats survived for 40 h, when the animals were kept at 5 degrees C without food. Five low molecular weight fractions obtained from Sprague Dawley rat sera were administered to analbuminemic rats kept under these conditions. The duration of survival was extended by the administration of two of the fractions. Several characteristics of one of these fractions coincided with those of uric acid, and body temperature of analbuminemic and Sprague Dawley rats increased within 5 min after uric acid administration. |
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Authors:
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T Kawaguchi; M Shimode; H Matsushita; S Nagase |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Japanese journal of physiology Volume: 36 ISSN: 0021-521X ISO Abbreviation: Jpn. J. Physiol. Publication Date: 1986 |
Date Detail:
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Created Date: 1986-09-22 Completed Date: 1986-09-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 2985184R Medline TA: Jpn J Physiol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 295-303 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Chemical Analysis Body Temperature / drug effects Chromatography Cold Temperature* Fasting* Female Rats Rats, Inbred Strains Serum Albumin / deficiency* Spectrophotometry Uric Acid / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Serum Albumin; 69-93-2/Uric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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