| Frequency and risk of noncardiac surgery after drug-eluting stent implantation. | |
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MedLine Citation:
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PMID: 20824750 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Few studies have described the frequency and risk of surgery after drug-eluting stent (DES) implantation. METHODS: The medical records of 827 consecutive patients who received a DES at our institution between January 1, 2005 and July 1, 2008 were retrospectively reviewed to determine the outcomes of patients who subsequently underwent noncardiac surgery. RESULTS: During a median follow-up of 21 months, 135 patients underwent 191 noncardiac surgeries. The incidence of noncardiac surgery was 7% at 1 year, 18% at 2 years, and 22% at 3 years. Mean age was 62 years and 96% were men. A perioperative complication occurred in 19 surgeries (10%): excessive bleeding in 11 patients (6%), myocardial infarction in four patients (2%), acute renal failure in one patient (0.5%), hypotension and syncope in one patient (0.5%) and postoperative death in three patients (1.6%). Stent thrombosis occurred in one patient (0.5%). A complication occurred in six of 58 surgeries (10%) in which patients received perioperative clopidogrel vs. 13 of 133 surgeries (10%) in which patients did not receive perioperative clopidogrel (P = 0.90). Complications occurred in three of 25 surgeries performed within 6 months (16%), in four of 37 surgeries performed between 6 and 12 months (11%), and in 12 of 129 surgeries performed after >12 months (9%) from DES implantation (P = 0.90). CONCLUSION: Noncardiac surgery is frequently needed in the years after DES implantation and appears to carry a low risk of stent thrombosis and perioperative complications. |
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Authors:
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Nainesh K Gandhi; Abdul-Rahman R Abdel-Karim; Subhash Banerjee; Emmanouil S Brilakis |
Publication Detail:
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Type: Journal Article Date: 2011-03-08 |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: 77 ISSN: 1522-726X ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-20 Completed Date: 2011-09-09 Revised Date: 2012-03-16 |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 972-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, Texas 75216, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Balloon, Coronary / adverse effects, instrumentation*, mortality Chi-Square Distribution Drug-Eluting Stents* Female Humans Kaplan-Meier Estimate Male Middle Aged Myocardial Infarction / etiology Platelet Aggregation Inhibitors / administration & dosage Postoperative Complications / etiology*, mortality Retrospective Studies Risk Assessment Risk Factors Surgical Procedures, Operative* / adverse effects, mortality Texas Thrombosis / etiology Ticlopidine / administration & dosage, analogs & derivatives Time Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Platelet Aggregation Inhibitors; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel |
| Comments/Corrections | |
Comment In:
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Catheter Cardiovasc Interv. 2012 Feb 15;79(3):498; author reply 499-500
[PMID:
21805612
]
Catheter Cardiovasc Interv. 2011 Jun 1;77(7):977-8 [PMID: 21598350 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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