Document Detail


Frequency of pulmonary hypertension in asymptomatic β-thalassemia major patients and the role of physiological parameters in evaluation.
MedLine Citation:
PMID:  20795768     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
In this study, the authors aimed to evaluate the frequency of pulmonary hypertension (PHT) in asymptomatic thalassemia major (TM) patients, and to investigate the impact of pulmonary function test (PFT) and CO diffusion results on the evaluation of pulmonary hypertension. Data from 50 asymptomatic patients with TM over age 10 were evaluated. Pulmonary hypertension was diagnosed in 10 patients (20%). High tricuspid regurgitant jet velocity was found in 14% of adults and in 25% of children. Pulmonary function test including CO diffusion testing results were not different between the TM patients with or without pulmonary hypertension. In conclusion, PHT was frequent among TM patients even they were asymptomatic and although PFT results has shown lack of association, it should be investigated in larger population.
Authors:
Goksel Kiter; Yasemin Isik Balci; Akin Ates; Sibel Hacioglu; Ismail Sari
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  27     ISSN:  1521-0669     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  597-607     Citation Subset:  IM    
Affiliation:
Department of Pulmonology, Pamukkale University, Faculty of Medicine, Denizli, Turkey.
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