Document Detail


Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease.
MedLine Citation:
PMID:  8213549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In sustained ventricular tachycardia (VT) unrelated to coronary artery disease, the incidence of reentry with an excitable gap was examined, and rapid pacing was performed to entrain VT in 48 episodes in 42 consecutive patients. Coronary artery disease was excluded by coronary arteriography. The underlying heart diseases were postoperative congenital heart diseases (n = 5), dilated (n = 7) or hypertrophic (n = 4) cardiomyopathy, arrhythmogenic right ventricular dysplasia (n = 6) and miscellaneous heart diseases (n = 5), as well as no demonstrable heart disease (n = 15) in which 8 patients had verapamil-responsive VT. Except for 1 patient with hypertrophic cardiomyopathy, 48 morphologically distinct monomorphic sustained VTs were induced. Twenty-five VTs showed right bundle branch block morphology and 23 left bundle branch block morphology, and VT was entrained in 84 and 96%, respectively. The overall incidence of the entrainment was 89.6% (43 of 48 monomorphic VTs), and the frequency of the ability to entrain VT ranged between 33.3 and 100% in the subgroups. The lowest frequency was found in hypertrophic cardiomyopathy. In conclusion, most inducible monomorphic sustained VT unassociated with coronary artery disease was presumed to be reentry with an excitable gap.
Authors:
Y Aizawa; N Naitoh; H Kitazawa; Y Kusano; H Uchiyama; T Washizuka; A Shibata
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  72     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-11-18     Completed Date:  1993-11-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  916-21     Citation Subset:  AIM; IM    
Affiliation:
First Department of Internal Medicine, Niigata University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Bundle of His / physiopathology
Bundle-Branch Block / physiopathology
Cardiac Pacing, Artificial / methods*
Cardiomyopathy, Dilated / physiopathology
Cardiomyopathy, Hypertrophic / physiopathology
Coronary Disease
Electrocardiography
Female
Heart Defects, Congenital / complications,  physiopathology
Heart Ventricles / abnormalities,  physiopathology
Humans
Male
Middle Aged
Tachycardia, Ventricular / drug therapy,  physiopathology,  therapy*
Verapamil / therapeutic use
Chemical
Reg. No./Substance:
52-53-9/Verapamil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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