| Frequency and outcomes of transient myocardial ischemia in critically ill adults admitted for noncardiac conditions. | |
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MedLine Citation:
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PMID: 14619356 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Critically ill adults admitted for noncardiac conditions are at risk for acute myocardial ischemia. OBJECTIVES: To detect myocardial ischemia and injury in patients admitted for noncardiac conditions and to examine the relationship of myocardial ischemia, injury, and acuity to cardiac events. METHODS: Transient myocardial ischemia, acuity, elevations in serum troponin I, and in-hospital cardiac events were examined in 76 consecutive patients. Transient myocardial ischemia, determined by using continuous electrocardiography, was defined as a 1-mm (0.1-mV) change in ST level from baseline to event in 1 or more leads lasting 1 or more minutes. Acuity was determined by scores on Acute Physiology and Chronic Health Evaluation II. RESULTS: A total of 37 ischemic events were detected in 8 patients (10.5%); 32 (86%) were ST-segment depressions, and 35 (96%) were silent. Twelve patients (15.8%) had elevated levels of troponin I. Transient myocardial ischemia, elevated troponin I levels, and advanced age were significant predictors of cardiac complications (R2 = 0.387, F = 15.2, P < .001). Acuity correlated only modestly with increased length of stay in the intensive care unit (r = 0.26, P = .02) and elevated troponin I levels (r = 0.25, P = .03). Patients with transient myocardial ischemia had significantly higher rates of elevations in troponin I (P < .001) and cardiac events (P < .001) than did patients without. CONCLUSIONS: Transient myocardial ischemia and advanced age are predictors of cardiac events and may indicate patients at risk for cardiac events. |
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Authors:
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Kathy J Booker; Karyn Holm; Barbara J Drew; Dorothy M Lanuza; Frank D Hicks; Tim Carrigan; Michelle Wright; John Moran |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of critical care : an official publication, American Association of Critical-Care Nurses Volume: 12 ISSN: 1062-3264 ISO Abbreviation: Am. J. Crit. Care Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-11-17 Completed Date: 2004-04-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9211547 Medline TA: Am J Crit Care Country: United States |
Other Details:
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Languages: eng Pagination: 508-16; discussion 517 Citation Subset: IM; N |
Affiliation:
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Millikin University, Decatur, Ill., USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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APACHE Age Factors Aged Aged, 80 and over Chi-Square Distribution Comorbidity Coronary Artery Disease / diagnosis, epidemiology Critical Illness Electrocardiography Female Hospitalization Humans Intensive Care Units Male Multivariate Analysis Myocardial Ischemia / diagnosis*, epidemiology* Prognosis Risk Factors Telemetry Troponin I / blood |
| Chemical | |
Reg. No./Substance:
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0/Troponin I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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