Document Detail


Frequency and intensity of behavioral and psychological symptoms in the course of Alzheimer's disease
MedLine Citation:
PMID:  11324386     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the study was: 1) to estimate the occurrence and intensity of some psychopathological symptoms in the course of Alzheimer's disease, and 2) to examine whether the occurrence of behavioral and psychological symptoms increases with the deepening of dementia process among persons with Alzheimer's disease living in their homes with outpatient treatment. The study was conducted among 94 persons (38 men and 56 women ageing from 52 to 86 years (x = 72.4 +/- 6.9), with education: from 2 to 17 years (x = 11.2 +/- 3.7). Three subgroups were selected for study with regard to the intensity of dementia process, estimated according to Clinical Dementia Rating (CDR): very mild (n = 16, x = 71.4 +/- 6.7), mild (n = 43, x = 72.6 +/- 7.9), moderate (n = 35, x = 72.5 +/- 6.9). Subjects in group II and III fulfill diagnostic criteria of dementia according to ICD-10, DSM IV and criteria of probable AD according to NINCDS-ADRDA. In the estimation of occurrence of behavioral and psychological disturbances: Alzheimer's Disease Assessment Scale--non-cognitive behavior (ADAS-non-cog) and subscale "Change in Personality, Interests, Drive" of Blessed Dementia Scale were used. The results have shown that with the progress of dementia process, the occurrence of the following psychopathological symptoms such as: hallucinations, intensive motor activity, purposeless hyperactivity, pacing, rigidity increases and there is a relinquishment of hobbies. In addition, regardless of the stage of dementia, such behaviors as: apathy, depression, tearfullness, impaired emotional control and disturbances of appetite were observed relatively frequently.
Authors:
B Wasiak; T Gabryelewicz; E Łuczywek; A Pfeffer; K Czyzewski; M Styczyńska; M Gołebiowski; W Matysiak; M Barcikowska
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Psychiatria polska     Volume:  35     ISSN:  0033-2674     ISO Abbreviation:  Psychiatr. Pol.     Publication Date:    2001 Jan-Feb
Date Detail:
Created Date:  2001-04-27     Completed Date:  2001-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0103314     Medline TA:  Psychiatr Pol     Country:  Poland    
Other Details:
Languages:  pol     Pagination:  93-107     Citation Subset:  IM    
Affiliation:
Zespołu Badawczo-Leczniczego Chorób Zwyrodnieniowych CUN CMDiK PAN/CSK MSWiA w Warszawie. bwasiak@cmdik.pan.pl
Vernacular Title:
Czestość oraz intensywność wystepowania zaburzeń psychicznych i zachowania w otepieniu o róznym nasileniu w przebiegu choroby Alzheimera.
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MeSH Terms
Descriptor/Qualifier:
Age Distribution
Aged
Aged, 80 and over
Alzheimer Disease / classification,  epidemiology*
Ambulatory Care / statistics & numerical data
Comorbidity
Disease Progression
Female
Humans
Male
Mental Disorders / epidemiology*
Middle Aged
Poland / epidemiology
Sex Distribution

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