Document Detail

Frequency of eosinophilia in adult T-cell leukemia/lymphoma.
MedLine Citation:
PMID:  1735088     Owner:  NLM     Status:  MEDLINE    
Cases of adult T-cell leukemia/lymphoma (ATLL) display several peculiar clinical features, including skin rash, hypercalcemia, and an increase in the absolute neutrophil count. The patients rarely have pronounced eosinophilia. In this study, the eosinophilia observed in lymphoproliferative disorders of 62 patients with ATLL, 27 with T-cell lymphoma (TL), and 19 with B-cell lymphoma (BL) was investigated. The incidence of eosinophilia (greater than or equal to 570/microliters) was higher in patients with ATLL than in patients with TL or BL. Thirteen patients with ATLL (21.0%), 3 with TL (11.1%), and 2 with BL (10.5%) had eosinophilia. Of these patients, three with ATLL and one with TL who had a pathologic diagnosis of immunoblastic lymphadenopathy (IBL) showed pronounced eosinophilia up to 10,934/microliters. Because the number of eosinophils in the peripheral blood of these patients correlated both with the number of ATLL cells and the degree of lymphadenopathy and because this fluctuated with chemotherapy, it seems likely that the secretion of some lymphokines by the lymphoma cells is responsible for the eosinophilia.
K Murata; Y Yamada; S Kamihira; S Atogami; K Tsukasaki; S Momita; T Amagasaki; N Sadamori; M Tomonaga; K Kinoshita
Related Documents :
8431918 - T(5;12)(q31;p12). a clinical entity with features of both myeloid leukemia and chronic ...
9180288 - Incidence and role of apoptosis in myelodysplastic syndrome: morphological and ultrastr...
17873758 - Angioimmunoblastic t-cell lymphoma: clinical and laboratory features at diagnosis in 77...
2178458 - Acute megakaryoblastic leukemia in children identified by immunological marker studies.
2566688 - Semirigid ureteroscopy: a new genre.
15585978 - Severe pulmonary hypertension in chronic idiopathic myelofibrosis.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  69     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-03-10     Completed Date:  1992-03-10     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  966-71     Citation Subset:  AIM; IM    
Department of Hematology, Atomic Disease Institute, Nagasaki University School of Medicine, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Eosinophilia / complications*
Leukemia, T-Cell / complications*,  drug therapy
Lymphoma, T-Cell / complications*,  drug therapy
Lymphoproliferative Disorders / complications*
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Familial microcephaly with normal intelligence in a patient with acute lymphoblastic leukemia.
Next Document:  Response of brain metastases from breast cancer to systemic chemotherapy.