Document Detail


Frequency of diastolic third and fourth heart sounds with myocardial ischemia induced during percutaneous coronary intervention.
MedLine Citation:
PMID:  19012901     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although the standard 12-lead electrocardiogram (ECG) is considered the gold standard to diagnose acute myocardial ischemia, nearly half of ECGs are nondiagnostic in patients who present with chest pain and have subsequent confirmation of infarction with positive serum biomarkers. METHODS: A prospective study was performed to investigate the frequency and intensity of diastolic third and fourth heart sounds (S3 and S4), as measured by computerized acoustic cardiography, with myocardial ischemia induced by balloon occlusion during percutaneous coronary intervention. RESULTS: In our 24 subjects, during percutaneous coronary intervention-induced ischemia, a new or increased intensity S3 or S4 developed in 67%. Ten (67%) of 15 patients without clinical ST criteria for ischemia also developed new or increased-intensity diastolic heart sounds. CONCLUSIONS: The combined use of diastolic heart sounds, as a measurement of ventricular dysfunction, with the standard ECG may improve the noninvasive diagnosis of myocardial ischemia that is likely to develop into infarction.
Authors:
Eunyoung Lee; Andrew D Michaels; Ronald H Selvester; Barbara J Drew
Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2008-11-14
Journal Detail:
Title:  Journal of electrocardiology     Volume:  42     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2009 Jan-Feb
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-02-27     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  39-45     Citation Subset:  IM    
Affiliation:
Department of Physiological Nursing, University of California, San Francisco, San Francisco, CA 94143-0610, USA. eunylee@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Angioplasty, Transluminal, Percutaneous Coronary*
Female
Heart Auscultation / methods*
Heart Sounds*
Humans
Male
Middle Aged
Myocardial Ischemia / complications,  diagnosis*,  physiopathology*,  surgery
Reproducibility of Results
Sensitivity and Specificity
Ventricular Dysfunction, Left / complications,  diagnosis*,  physiopathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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