Document Detail


Frequency analysis in different types of paroxysmal atrial fibrillation.
MedLine Citation:
PMID:  16580528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: This study sought to investigate the regional frequency distribution from multiple bi-atrial sites in different types of paroxysmal atrial fibrillation (AF). BACKGROUND: A previous study showed a left atrium (LA) to right atrium (RA) frequency gradient in patients with paroxysmal AF. METHODS: Forty-four patients (age = 60 +/- 16, male patients = 27) with paroxysmal AF originating from the pulmonary veins (PVs) (n = 31) or superior vena cava (SVC) (n = 13) were included. Frequency analysis was performed on the intracardiac electrograms (7 s, 1 kHz/channel) recorded from PV, posterior LA, coronary sinus (CS), posterolateral RA, and SVC. The largest peak frequency was identified as the dominant frequency (DF). RESULTS: In the PV-AF patients, there was a frequency gradient from the PV ostium to the LA, RA, and SVC (8.5 +/- 3.3 Hz vs. 5.9 +/- 1.1 Hz vs. 5.2 +/- 0.85 Hz vs. 5.5 +/- 0.48 Hz, respectively, p < 0.001). The highest DFs were mostly located at the arrhythmogenic PV ostium (58%). The DFs of the arrhythmogenic PV and PV ostium were significantly higher than those of the non-arrhythmogenic PVs and PV ostia (p < 0.05). In the SVC-AF patients, there was a frequency gradient from the SVC to the RA, LA, and PV (8.0 +/- 2.4 Hz vs. 5.9 +/- 1.1 Hz vs. 5.9 +/- 0.7 Hz vs. 5.8 +/- 0.7 Hz, respectively, p = 0.001). The highest DFs were mostly located inside the SVC (77%) instead of the SVC ostium (as compared with PV-AF patients, p = 0.035). CONCLUSIONS: The location of the highest DF depended on the arrhythmogenic PV or SVC. A frequency gradient was present between the arrhythmogenic thoracic vein and atrium in all patients.
Authors:
Yenn-Jiang Lin; Ching-Tai Tai; Tsair Kao; Han-Wen Tso; Satoshi Higa; Hsuan-Ming Tsao; Shih-Lin Chang; Ming-Hsiung Hsieh; Shih-Ann Chen
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Publication Detail:
Type:  Journal Article     Date:  2006-03-15
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  47     ISSN:  1558-3597     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-05-26     Revised Date:  2006-06-08    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1401-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / classification*,  diagnosis,  physiopathology*
Atrial Function*
Coronary Vessels / physiopathology
Electrophysiologic Techniques, Cardiac*
Female
Humans
Male
Middle Aged
Pulmonary Veins / physiopathology
Time Factors
Vena Cava, Superior / physiopathology
Comments/Corrections
Comment In:
J Am Coll Cardiol. 2006 Apr 4;47(7):1408-9   [PMID:  16580529 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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