Document Detail


Frequency tuning in the tone burst-evoked myogenic potentials in extraocular muscles in normal human subjects.
MedLine Citation:
PMID:  20828510     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In this cross-sectional study, we investigated the frequency tuning properties of sound-evoked vestibular myogenic potentials in extraocular muscles (OVEMPs) in normal human subjects.
METHODS: Acoustic tone bursts (130 dB pSPL, 10 ms plateau, 1 ms rise/fall) with nine frequencies from 125 to 4000 Hz were presented monoaurally to 12 normal subjects while they sat upright and maintained centre gaze. Using surface electrodes, the OVEMPs were recorded at four locations surrounding the contralateral eye (superior, inferior, nasal, and temporal) and were referenced to an electrode placed at the nape of the neck over C7. To measure the amplitudes of the OVEMP, signals from the electrodes were amplified and sampled at 10 kHz and were averaged over 250 repetitions.
RESULTS: We found that the OVEMPs recorded at the four sites exhibited similar well-defined frequency tuning with peak amplitude at ≈ 1000 Hz.
CONCLUSION: Although several studies have examined the frequency tuning of the vestibular evoked myogenic potential measured from the sternocleidomastoid muscles (SVEMP), the reported results are quite variable as regards frequency, which produces peak amplitude. The well-defined OVEMP frequency tuning provides an alternative to the SVEMP for assessing vestibular function via acoustic stimulation. Further studies are needed to identify the extent to which each of the five vestibular end-organs is activated by sound and their contribution to the sound-evoked vestibular myogenic potentials.
Authors:
Andrea Lewis; William Mustain; Youguo Xu; Thomas Eby; Wu Zhou
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale     Volume:  39     ISSN:  1916-0216     ISO Abbreviation:  J Otolaryngol Head Neck Surg     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2011-02-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101479544     Medline TA:  J Otolaryngol Head Neck Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  491-7     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Adult
Cross-Sectional Studies
Electrodes
Electromyography / methods*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Neck Muscles / physiology*
Oculomotor Muscles / physiology*
Reference Values
Vestibular Evoked Myogenic Potentials / physiology*
Vestibule, Labyrinth / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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