Document Detail


Frequency of Radial Artery Occlusion After Transradial Access in Patients Receiving Warfarin Therapy and Undergoing Coronary Angiography.
MedLine Citation:
PMID:  24210677     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The efficacy of warfarin-induced anticoagulation in reducing radial artery occlusion (RAO) after transradial access is not known. The present case-control study compared the incidence of early (24 hours) and late (30 days) RAO in patients undergoing transradial diagnostic coronary angiography during therapeutic warfarin anticoagulation (group 1) with that of a matched (3:1) cohort of patients not receiving warfarin and receiving intraprocedural heparin (group 2). All patients underwent transradial diagnostic coronary angiography using a 5F hydrophilic introducer sheath. The patients in group 2 received an intravenous heparin bolus (50 IU/kg) immediately after sheath insertion. After sheath removal, hemostasis was obtained using the TR-band (Terumo Interventional Systems, Terumo Medical, Tokyo, Japan) and a plethysmography-guided patent hemostasis technique. We included 86 patients receiving warfarin with an international normalized ratio of 2 to 4 in group 1 and 250 matched patients in group 2. No significant differences were present in the demographic and procedural variables between the 2 groups. Early RAO occurred in 18.6% of the patients in group 1 compared with 9.6% of patients in group 2 (p = 0.024). The incidence of late RAO remained significantly higher in group 1 compared with group 2 (13.9% vs 5.2%, p = 0.01). All patients with RAO remained asymptomatic. In conclusion, patients receiving chronic oral anticoagulation with warfarin and undergoing transradial coronary angiography without parenteral anticoagulation had a higher incidence of early and late RAO compared with patients receiving standard intravenous heparin therapy.
Authors:
Samir B Pancholy; Imdad Ahmed; Olivier F Bertrand; Tejas Patel
Related Documents :
24329567 - Continuous renal replacement therapy reduces the systemic and pulmonary inflammation in...
24281047 - Release from glomerular overload by the addition of low-dose thiazide in patients with ...
23691697 - Tenofovir disoproxil fumarate-associated nephrotoxicity in hiv-infected patients: a pro...
23324167 - Cardiac and hepatic iron and ejection fraction in thalassemia major: multicentre prospe...
9870617 - The non-specific effect of endolymphatic sac surgery in treatment of meniere's disease:...
114017 - Radiographic evaluation of the spine after surgical correction of scoliosis.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-5
Journal Detail:
Title:  The American journal of cardiology     Volume:  -     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-11-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Affiliation:
The Wright Center for Graduate Medical Education and The Commonwealth Medical College, Scranton, Pennsylvania. Electronic address: pancholys@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison of Outcomes in Patients ?85 Versus >85 Years of Age Undergoing Transcatheter Aortic-Valve...
Next Document:  Renal artery calcium, cardiovascular risk factors, and indexes of renal function.