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The Frequency of Insufficient Contrast Enhancement of the Pulmonary Artery in Routine Contrast-enhanced Chest CT and Its Improvement With an Increased Injection Rate: A Prospective Study.
MedLine Citation:
PMID:  20463614     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: To evaluate the frequency of insufficient contrast enhancement of the pulmonary artery (PA) during chest computed tomography (CT) and its improvement by an increased injection rate.
MATERIALS AND METHODS: Two hundred and eighty-eight (group A) and 278 (group B) consecutive patients underwent chest CT with the administration of 100 mL of a 300-mgI/mL nonionized contrast material through the antecubital vein using a power injector. The flow rate was 2 mL/s in group A and 3 mL/s in group B, and 50 mL saline was administered simultaneously using a dual injector. The scan delay was 30 s in both groups. The CT numbers in the pulmonary trunk, bilateral main PA, left atrium, and ascending and descending aortas were measured. Insufficient enhancement of the PA was defined as a CT number of the pulmonary trunk ≤180 HU.
RESULTS: Insufficient enhancement of the PA was observed in 21 of 288 patients (7.3%) in group A, whereas it was seen in only 9 of 278 patients (3.2%) in group B (P=0.038).
CONCLUSIONS: The use of a flow rate of 3 mL/s is associated with a significantly lower frequency of insufficient contrast enhancement of the PA, compared with the use of a lower flow rate of 2 mL/s with the same total volume of contrast.
Authors:
Yoshiyuki Ozawa; Masaki Hara; Yuta Shibamoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of thoracic imaging     Volume:  26     ISSN:  1536-0237     ISO Abbreviation:  J Thorac Imaging     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606160     Medline TA:  J Thorac Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  42-7     Citation Subset:  IM    
Affiliation:
Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
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