Document Detail


Frequency-dependent attentional modulation of local field potential signals in macaque area MT.
MedLine Citation:
PMID:  20484646     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Visual attention modulates neuronal responses in primate motion processing area MT. However, whether it modulates the strength local field potentials (LFP-power) within this area remains unexplored, as well as how this modulation relates to the one of the neurons' response. We investigated these issues by simultaneously recording LFPs and neuronal responses evoked by moving random dot patterns of varying direction and contrast in area MT of two male monkeys (Macaca mulatta) during different behavioral conditions. We found that: (1) LFP-power in the gamma (30-120 Hz), but not in the delta (2-4 Hz), (4-8 Hz), alpha (8-12 Hz), beta(1) (12-20 Hz), and beta(2) (20-30 Hz) frequency bands, was tuned for motion direction and contrast, similarly to the neurons' response, (2) shifting attention into a neuron's receptive field (RF) decreased LFP-power in the bands below 30 Hz (except the band), whereas shifting attention to a stimulus motion direction outside the RF had no effect in these bands, (3) LFP-power in the gamma band, however, exhibited both spatial- and motion direction-dependent attentional modulation (increase or decrease), which was highly correlated with the modulation of the neurons' response. These results demonstrate that in area MT, shifting attention into the RFs of neurons in the vicinity of the recording electrode, or to the direction of a moving stimulus located far away from these RFs, distinctively modulates LFP-power in the various frequency bands. They further suggest differences in the neural mechanisms underlying these types of attentional modulation of visual processing.
Authors:
Paul S Khayat; Robert Niebergall; Julio C Martinez-Trujillo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  30     ISSN:  1529-2401     ISO Abbreviation:  J. Neurosci.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-06-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7037-48     Citation Subset:  IM    
Affiliation:
Cognitive Neurophysiology Laboratory, Department of Physiology, McGill University, Montr?al, Qu?bec H3G 1Y6, Canada. paul.khayat@mcgill.ca
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MeSH Terms
Descriptor/Qualifier:
Action Potentials / physiology*
Analysis of Variance
Animals
Attention / physiology*
Biophysical Processes / physiology*
Electroencephalography / methods
Evoked Potentials / physiology*
Fixation, Ocular
Macaca mulatta
Male
Motion Perception / physiology
Neurons / physiology
Photic Stimulation / methods
Psychomotor Performance / physiology
Reaction Time / physiology
Spectrum Analysis / methods
Temporal Lobe / cytology,  physiology*
Visual Fields / physiology
Grant Support
ID/Acronym/Agency:
//Canadian Institutes of Health Research

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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