Document Detail

Frequency of conduction disturbances after transcatheter implantation of an Edwards Sapien aortic valve prosthesis.
MedLine Citation:
PMID:  20723650     Owner:  NLM     Status:  MEDLINE    
We evaluated the incidence of conduction abnormalities and requirement for permanent pacemaker in patients undergoing transcatheter aortic valve implantation (TAVI) with the Edwards Sapien prosthesis. In 2009, >8,000 patients were treated with TAVI using 1 of the 2 commercialized models of bioprosthesis (Edwards Sapien, Edwards Lifesciences, Irvine, California; and CoreValve, Medtronic, Irvine, California). Occurrence of conduction abnormalities including complete atrioventricular block requiring permanent pacemaker has been reported after TAVI with the 2 models of valve, more frequently with the CoreValve. We analyzed standard 12-lead electrocardiograms of 69 consecutive patients in whom an Edwards Sapien prosthesis was successfully implanted. Electrocardiograms were examined before treatment, at day 1, and at 1-month follow-up. Heart rate, PR and QT intervals and QRS duration were measured and the presence of a first-, second-, or third-degree atrioventricular block was documented. There was a slight increase in heart rate and a discrete decrease in QT interval at day 1. These values had returned to baseline values at 1 month. There was no change in PR interval but a transitory increase in QRS duration was noted. Frequency of left bundle branch block increased from 14.5% at baseline to 27.5% at day 1 with a decreased incidence at day 30 (21.3%). Permanent pacemaker was required in only 3 patients (4.3%). In conclusion, in our experience, conductive disorders and requirement of a definitive pacemaker after implantation of an Edwards Sapien aortic bioprosthesis are infrequent. The physical properties of this prosthesis may explain this observation.
Matthieu Godin; Helene Eltchaninoff; Akira Furuta; Christophe Tron; Frederic Anselme; Karim Bejar; Carlos Sanchez-Giron; Fabrice Bauer; Pierre-Yves Litzler; Jean-Paul Bessou; Alain Cribier
Publication Detail:
Type:  Journal Article     Date:  2010-07-23
Journal Detail:
Title:  The American journal of cardiology     Volume:  106     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-20     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  707-12     Citation Subset:  AIM; IM    
Copyright Information:
2010. Published by Elsevier Inc.
Department of Cardiology, Rouen University Hospital and INSERM U, University of Rouen, France.
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MeSH Terms
Aged, 80 and over
Aortic Valve Stenosis / complications,  physiopathology,  therapy*
Balloon Dilatation / adverse effects
Bioprosthesis / adverse effects*
Cohort Studies
Heart Block / epidemiology*
Heart Catheterization / adverse effects*
Heart Valve Prosthesis / adverse effects*
Heart Valve Prosthesis Implantation / adverse effects*
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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