| Freezing increment in keratophakia. | |
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MedLine Citation:
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PMID: 3915238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In homoplastic keratomileusis, keratophakia, and epikeratophakia, the corneal tissue that provides the final refractive lenticule undergoes a conformational change when frozen. Because corneal tissue is composed primarily of water, an assumed value of 9.08% (approximate volumic percentage expansion of water when frozen) is frequently used for the increase in thickness, or freezing increment, rather than measuring it directly. We evaluated 32 cases of clinical keratophakia and found the increase in thickness to average 37 +/- 21%. In this series of 32 cases, the percentage of patients with a greater than 4 D residual refractive error was 16%. If an assumed freezing increment of 9.08% had been used, the percentage would have been 28%, with two-thirds of these 28% manifesting a marked undercorrection. Because of a lack of studies documenting the behavior of corneal tissue following cryoprotection and freezing, it is suggested that measurements be taken during homoplastic surgery to minimize the potential for significant inaccuracy in obtaining the desired optic result. |
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Authors:
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C A Swinger; H J Wisnicki |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Cornea Volume: 4 ISSN: 0277-3740 ISO Abbreviation: Cornea Publication Date: 1985-1986 |
Date Detail:
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Created Date: 1986-07-30 Completed Date: 1986-07-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8216186 Medline TA: Cornea Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 225-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Corneal Transplantation* Freezing* Humans Refraction, Ocular Refractive Surgical Procedures* |
| Grant Support | |
ID/Acronym/Agency:
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03346//PHS HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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