Document Detail

Freeze-fracture studies of myofiber plasma membrane in X chromosome-linked muscular dystrophy (mdx) mice.
MedLine Citation:
PMID:  3407395     Owner:  NLM     Status:  MEDLINE    
The structure of the muscle plasma membrane of extensor digitorum longus muscles of X chromosome-linked muscular dystrophy (mdx) mice was studied by freeze-fracture technique at several time points after birth. The common denominator of the abnormalities was the decreased density of orthogonal arrays throughout all the time points examined. The results demonstrated that the ultrastructural features of the muscle plasma membrane alterations in mdx mice were similar to those in Duchenne dystrophy.
S Shibuya; Y Wakayama
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neuropathologica     Volume:  76     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1988  
Date Detail:
Created Date:  1988-09-15     Completed Date:  1988-09-15     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  179-84     Citation Subset:  IM    
Department of Medicine, Showa University, Fujigaoka Hospital, Yokohama, Japan.
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MeSH Terms
Age Factors
Freeze Fracturing
Muscle Development
Muscles / ultrastructure*
Muscular Dystrophy, Animal / genetics,  pathology*
Sex Chromosome Aberrations*
X Chromosome

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