Document Detail

Free thiomalate levels in patients with rheumatoid arthritis treated with disodium aurothiomalate: relationship to clinical outcome of therapy.
MedLine Citation:
PMID:  6437348     Owner:  NLM     Status:  MEDLINE    
Sixteen patients with seropositive rheumatoid arthritis were treated with 20 mg disodium aurothiomalate (Myocrisin) weekly for six months. Disease activity was assessed before and after treatment. Plasma profiles and urinary excretion of free thiomalate were measured in all patients after the initial injection and again at six months in the 12 patients remaining on therapy. No difference was found in plasma levels or urinary excretion of free thiomalate between patients who responded to treatment or who developed toxic reactions and those who did not.
S R Rudge; D Perrett; A J Swannell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  43     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-11-30     Completed Date:  1984-11-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  698-702     Citation Subset:  IM    
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MeSH Terms
Arthritis, Rheumatoid / drug therapy,  metabolism*,  physiopathology
Blood Sedimentation
Gold Sodium Thiomalate / therapeutic use*
Hemoglobins / analysis
Middle Aged
Thiomalates / metabolism*
Time Factors
Reg. No./Substance:
0/Hemoglobins; 0/Thiomalates; 12244-57-4/Gold Sodium Thiomalate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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