| Free thiomalate levels in patients with rheumatoid arthritis treated with disodium aurothiomalate: relationship to clinical outcome of therapy. | |
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MedLine Citation:
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PMID: 6437348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sixteen patients with seropositive rheumatoid arthritis were treated with 20 mg disodium aurothiomalate (Myocrisin) weekly for six months. Disease activity was assessed before and after treatment. Plasma profiles and urinary excretion of free thiomalate were measured in all patients after the initial injection and again at six months in the 12 patients remaining on therapy. No difference was found in plasma levels or urinary excretion of free thiomalate between patients who responded to treatment or who developed toxic reactions and those who did not. |
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Authors:
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S R Rudge; D Perrett; A J Swannell |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of the rheumatic diseases Volume: 43 ISSN: 0003-4967 ISO Abbreviation: Ann. Rheum. Dis. Publication Date: 1984 Oct |
Date Detail:
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Created Date: 1984-11-30 Completed Date: 1984-11-30 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372355 Medline TA: Ann Rheum Dis Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 698-702 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arthritis, Rheumatoid / drug therapy, metabolism*, physiopathology Blood Sedimentation Female Gold Sodium Thiomalate / therapeutic use* Hemoglobins / analysis Humans Male Middle Aged Thiomalates / metabolism* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 0/Thiomalates; 12244-57-4/Gold Sodium Thiomalate |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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